Treatment Marble Bone Disease

Osteogenesis imperfecta or brittle bone disease is a group of hereditary connective tissue disorders characterized by unusual bone fragility and tendency to fracture.

Treatment marble bone disease.

This condition in turn leads to bones getting dissolved and ultimately break. Find diagnosis treatment and prevention information on more than 20 different muscle and bone diseases and conditions affecting the musculoskeletal system. Osteogenesis imperfecta congenita which is apparent at birth and osteogenesis imperfecta tarda which manifests itself usually in early childhood with milder. Introduction osteopetrosis is a disorder characterized by defective or absent osteoclasts the cells that resorb bone was first described in 1904 by heinrich albers schenberg.

Traditionally the disease has been recognized in two forms. Marble bone disease rare disorder in which the bones become extremely dense hard and brittle. Marble bone disease description causes and risk factors. Osteopetrosis or marble bone disease this is an extremely rare genetic disorder of the bones in which the bones get harder and denser.

The mass of bone increases but the new bone material. The disease progresses as long as bone growth continues. Marble bone disease causes short stature cerebral calcification and mental retardation. Osteopetrosis literally stone bone also known as marble bone disease or albers schönberg disease is an extremely rare inherited disorder whereby the bones harden becoming denser in contrast to more prevalent conditions like osteoporosis in which the bones become less dense and more brittle or osteomalacia in which the bones soften.

Marble bone disease when there is a failure in bone resorption. Marble this disease named for two reasons. Osteopetrosis refers to a group of rare inherited skeletal disorders characterized by increased bone density and abnormal bone growth. The musculoskeletal system consists of the body s bones muscles tendons ligaments joints cartilage.

The marrow cavities become filled with compact bone. Osteopetrosis marble bone disease osteopetrosis tarda albers schonberg disease. The most informative tool in determining the presence of marble disease is an x ray. Because increased bone mass crowds the bone marrow resulting in a reduced amount of marrow.

Symptoms and severity can vary greatly ranging from neonatal onset with life threatening complications such as bone marrow failure to the incidental finding of osteopetrosis on x ray depending on severity and age of onset features may include fractures. Bone marrow transplant is the only chance for survival in patients with osteopetrosis congenita.